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Infertility
Infertility: Understanding the Causes, Tests and Treatment Options
By Dr. Mehak Khalid•August 8, 2026
Infertility: Understanding the Causes, Tests and Treatment Options
What is infertility?
Infertility means difficulty achieving pregnancy despite having regular unprotected sexual intercourse.
Generally, couples are advised to seek an infertility evaluation if pregnancy has not occurred after:
- 12 months of regular unprotected intercourse when the woman is under 35 years old.
- 6 months when the woman is 35 years or older.
However, you should seek medical advice earlier if you have irregular or absent periods, known PCOS or endometriosis, previous pelvic surgery, recurrent miscarriage, suspected male fertility problems, or any other condition that may affect fertility.
Infertility is a medical condition—not anyone's fault. It can affect either partner, both partners, or sometimes no definite cause is identified.
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What causes infertility?
Fertility depends on several factors, including ovulation, egg quality, sperm, fallopian tubes, the uterus and timing of intercourse.
Common causes in women include:
🔹 Irregular or absent ovulation
🔹 PCOS
🔹 Increasing age and reduced ovarian reserve
🔹 Endometriosis
🔹 Blocked or damaged fallopian tubes
🔹 Fibroids or other uterine problems
🔹 Previous pelvic infections or surgery
🔹 Hormonal disorders
Causes in men may include:
🔹 Low sperm count
🔹 Poor sperm movement
🔹 Abnormal sperm shape
🔹 Hormonal problems
🔹 Previous infections or surgery
🔹 Certain medications, lifestyle factors or medical conditions
In some couples, all routine investigations may be normal. This is called unexplained infertility.
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Does infertility always mean IVF is needed?
No.
IVF is only one of several fertility treatment options.
Depending on the cause, treatment may include:
- Lifestyle modification
- Treatment of hormonal problems
- Ovulation induction
- Timed intercourse
- Intrauterine insemination (IUI)
- Surgery in selected cases
- IVF or ICSI
The correct treatment depends on the individual couple.
There is no single fertility treatment that is best for everyone.
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What tests are usually done?
A fertility assessment should generally involve both partners.
For the woman, the doctor may assess:
🩺 Menstrual history and ovulation
🩸 Hormonal and metabolic tests when appropriate
🩺 Ovarian reserve when indicated
📱 Pelvic ultrasound
🩻 Fallopian tube assessment when appropriate
For the man, a semen analysis is usually an important first investigation.
Additional tests are recommended only when clinically indicated.
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When should you consider IVF?
IVF may be considered when:
- Fallopian tubes are blocked or severely damaged
- Certain severe male-factor problems are present
- Previous fertility treatments have not been successful
- Endometriosis or other conditions significantly affect fertility
- There is a need for certain genetic or fertility-preservation strategies
- Other treatments are unlikely to be effective or appropriate
The decision should be individualized after assessing the couple's age, fertility history, investigations and treatment goals.
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What is ICSI?
ICSI (Intracytoplasmic Sperm Injection) is a laboratory technique used during IVF.
Instead of allowing sperm to fertilize the egg naturally in the laboratory, an embryologist injects a single sperm directly into the egg.
ICSI can be particularly useful in selected cases of male-factor infertility or previous fertilization problems.
However, ICSI is not automatically necessary for every IVF patient.
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Does age affect fertility?
Yes.
Female fertility gradually declines with age, and the decline becomes more significant as women approach their late 30s and 40s.
Age can affect both:
- The number of available eggs
- The likelihood of chromosomal abnormalities in embryos
This is why women who are older than 35 and trying to conceive should generally seek fertility evaluation sooner rather than waiting for a full year.
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What can you do to improve your fertility?
There is no guaranteed "fertility diet" or supplement that can overcome every cause of infertility.
However, healthy habits can support overall reproductive and metabolic health:
🥗 Eat a balanced diet
🏃 Stay physically active
⚖️ Maintain a healthy weight where possible
🚭 Avoid smoking
🍷 Avoid or limit alcohol
😴 Maintain adequate sleep
💊 Take medications and supplements only when appropriate
🩺 Manage conditions such as diabetes and thyroid disorders
For women planning pregnancy, discuss folic acid supplementation with your healthcare provider.
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Don't blame yourself
Infertility can be emotionally exhausting. Many couples experience anxiety, frustration, guilt or pressure from family and society.
Remember:
Infertility is not a failure.
It is a medical problem that deserves proper evaluation and evidence-based treatment.
Avoid comparing your fertility journey with someone else's. The fact that another person became pregnant after a particular treatment does not mean the same treatment is appropriate for you.
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When should you see a fertility specialist?
Consider a fertility consultation if:
🔸 You have been trying to conceive without success
🔸 Your periods are irregular or absent
🔸 You have known PCOS or endometriosis
🔸 You have had previous pelvic surgery or infections
🔸 You have experienced recurrent miscarriages
🔸 Your partner has an abnormal semen analysis
🔸 You are concerned about declining fertility because of age
🔸 You want to understand your fertility options before starting treatment
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The most important message
Infertility should be investigated systematically—not treated with guesswork.
A proper fertility assessment looks at both partners and identifies the most likely cause before deciding on treatment.
You do not always need IVF, and you should not feel pressured into IVF without understanding why it has been recommended.
Understand the cause → choose the appropriate treatment → make an informed decision.
If you are concerned about your fertility, a personalized consultation can help you understand your medical history, investigations and available treatment options.
This article is intended for general patient education and does not replace an individual medical consultation, examination or diagnosis.
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Full guide coming soon
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